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“Under the microscope you see a lot of inflammatory infiltrate in the adipose tissue,” Coviello said.

The researchers are investigating, among other things, how hormone treatment affects skeletal muscle gene expression and the mechanisms behind changes in adipose tissue.

Unlike carbohydrates, which are stored in muscle and liver as glycogen, and fats, which are stored in adipose tissue, we have nowhere to store excess protein/amino acids.

Major sources of this fat include adipose tissue as well as fatty acids the liver makes in response to insulin resistance and excess caloric intake.

The researchers found that as mice age and neurons in the hypothalamus become less active, sympathetic nerves pull back from white adipose tissue.