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This condition, called albuminuria, is a sign that the kidneys are not functioning normally.

They recommend that therapy should be considered at the higher level in people at high risk for stroke, retinopathy, and progression of albuminuria.

He writes that these “failed” trials “suggest that improvement in surrogate markers — lower blood pressure or less albuminuria — does not translate into risk reduction.”

According to Parkes,18 who closely observed six cases with the view of determining this question, albuminuria does not occur at any stage of the disease.

Bright in his study of albuminuria and contracted kidney practically taught us no more than this, except that he added the further symptom of the presence of albumin in the urine.