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The results, published today in The Lancet, showed that patients taking amitriptyline were almost twice as likely to report an overall improvement in symptoms as those taking a placebo.

Among the drugs studied - which included Prozac and a cheap antidepressant called amitriptyline - only one, called duloxetine, showed any evidence for pain relief.

The researchers randomized the children into three groups that received a placebo, the antidepressant amitriptyline or the antiepileptic medication topiramate.

The 500 test patients will be given either amitriptyline or a placebo tablet for six months and their symptoms and mood checked regularly.

Mr Saffery, a former youth rugby player for London Irish, was diagnosed with depression in January 2018 and was prescribed amitriptyline.