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He died of complications from aortic insufficiency, said his companion, Susan Swift.

Zangrillo said a team of doctors at the multi-disciplinary San Raffaele clinic ran a battery of tests and diagnosed a severe case of aortic insufficiency, which involves a leaking of the aortic valve of the heart, causing blood to flow in the reverse direction.

Zangrillo said a team of doctors at Milan's San Raffaele clinic ran a battery of tests and diagnosed a serious case of aortic insufficiency, which describes the leaking of the aortic valve of the heart causing blood to flow in the reverse direction.

She had developed scoliosis, or spinal curvature; an aortic insufficiency; and bursitis in one leg.

Low diastolic pressure is frequently pathognomonic of aortic insufficiency.