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Led by Professor Jack Cuzick at Queen Mary University of London, an international team of authors from the UK, Australia, Finland, Germany, Italy, and the USA tested whether measuring oestrogen in the blood could identify which women at increased risk of breast cancer will benefit most from the preventive effects of an aromatase inhibitor.

As a specialist in breast cancer, Dr. Schapira has treated women who decline postoperative therapy with a drug like tamoxifen or an aromatase inhibitor because they read on the web that the treatments are harmful, despite extensive studies showing they can help prevent a breast cancer recurrence.

If that is the case, a low dose of an aromatase inhibitor may be needed.

They only need to be taken once a day, alongside an aromatase inhibitor - which blocks the production of the hormone oestrogen and can fuel some breast cancers.

In 1979, they moved to Maryland — Angela went to the University of Maryland School of Medicine in Baltimore, where she continued the aromatase inhibitor work with an eye to moving it into clinical testing.