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To describe this phenomenon, the research team coined a new phrase: "amyloid-removal-related pseudo-atrophy" or ARPA.

"For example, you could try to make the HIV capsid less elastic, which our data suggests would hamper its ability to get inside the nucleus," said Arpa Hudait, a research scientist at UChicago and first author of the paper.

"This gives us a lot of confidence that we continue to be on track to hit the minimum $5 billion we have in previously signed advanced purchase agreements," Moderna Chief Commercial Officer Arpa Garay told Reuters.

A: When you hear someone call for an ARPA, what you are hearing is a cry for R&D that provides solutions to very hard problems.

"ARPA began funding heroic research projects that supported many of the innovations that emerged within the digital technology thread," Kleinrock told Salon.