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We use an animal model for multiple sclerosis, and we showed that you can use tolerization to treat an autoimmune disease if the mRNA codes for the autoantigen.

We use an animal model for multiple sclerosis, and we showed that you can use tolerization against an autoimmune disease if the mRNA codes for the autoantigen.

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.

The source of autoantigen that drives disease onset and progression is unclear.

Among other things, GAD is an autoantigen, which activates a subset of T cells that react to GAD as an ally rather than an enemy.