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base-pairing
[ beys-pair-ing ]
noun
- the process of binding separate DNA sequences by base pairs.
base pairing
noun
- biochem the hydrogen bonding that occurs between complementary nitrogenous bases in the two polynucleotide chains of a DNA molecule
base-pairing
- The hydrogen bonding of complementary nitrogen bases, one purine and one pyrimidine. Base-pairing occurs between the complementary strands of a DNA molecule or a DNA/RNA hybrid, and in the complementary pairing of codons and anticodons during the process of translation.
Example Sentences
When the complementary DNA strand pairs with the RecA-coated presynaptic single-stranded DNA, it also adopts this extended conformation and is stabilized mainly by base-pairing interactions with the presynaptic DNA.
In this case, the structure is further stabilized by binding of the displaced strand to the secondary DNA-binding site, as well as by base-pairing interactions between the complementary strand and the presynaptic single-stranded DNA.
This might help to ensure the quick formation of optimal base-pairing interactions in the primary DNA-binding site.
In addition, once a correct sequence match is found, the binding asymmetry might help to propagate strand invasion by further opening up enough double-stranded DNA to help establish the base-pairing associated with the next RecA protein in the filament.
Although U has the same base-pairing properties as does T, it belongs in RNA.
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