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"The screen was only possible because of recent progress made by our group and others in using C. elegans to study RQ-dependent metabolism, and our collaboration with RIKEN, one of Japan's biggest research agencies. We screened their world-class collection of 25,000 natural compounds, resulting in our discovery of a family of benzimidazole compounds that kills worms relying on this type of metabolism."

Kaplan also tested for benzimidazole tolerance in worms from Worthy's housemate and from another retired greyhound, both of whom had histories of stubborn infections, and found that they were resistant.

And the CDC warned that a new drug variety known as benzimidazole opioids has “begun appearing in cities across the country … adding a new threat to public health.”

By sequencing the tapeworm's genome, they pinpointed genes that provide resistance to a drug called benzimidazole, and other genes that suggest a possible sensitivity to another tapeworm drug, praziquantel.