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This batch provided an answer: He had hereditary spherocytosis, a disease in which the red blood cells were tiny spheres rather than the usual biconcave discs.

They are compact, flexible and shaped like biconcave disks, which helps them slip through narrow capillaries and gives them a high volume-to-surface area ration, so they can hold a lot of hemoglobin and oxygen.

The viewer observes Mr. Jacobs’s teeming green worlds through a custom-ordered biconcave lens.

Kolios' team's method works best with red blood cells because of their biconcave shape, which gives them the unique ability to absorb light better than platelets and white blood cells.

The vertebrae are biconcave, and although the gills are lost in the adult, ossified gill-arches, two to four in number, persist.