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We tested the hypothesis that an AR agonist could reduce osteoclast-mediated bone resorption in a murine calvaria model of wear particle–induced bone resorption.

The head consists of the calvaria, or part covered with hair, which is divided into three regions, the bregma or fore part, the crown, and the occiput.

CALVARY, the conventional English rendering of the calvaria of the Vulgate, the Latin version of the Greek κράνιον, both meaning “skull” and representing the Hebrew Golgotha, the name given to the scene of Christ’s crucifixion.

They are all more or less distorted in a discoidal manner, one by pressure over the frontal sinus, reducing the calvaria to a disk.