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Researchers found that the brain region associated with positive rewards, the caudate nucleus, was most activated by the scent of their familiar human; the study was published in the journal Behavioural Processes in 2014.

One study used MRI imaging to study activity in the caudate nucleus, a brain area associated with the expectation of a reward.

Some studies suggest that people with autism and people with OCD both have an unusually large caudate nucleus, a structure within the striatum.

These included the caudate nucleus, part of the reward system, and an ancient brain area called the ventral tegmental area, or VTA.

Five newly identified genetic variants influenced the size of two regions, the putamen and caudate nucleus, the team reported in 2015 in Nature.