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"Studies in humans are clearly required. Regarding intense light therapy, chronotherapy and restricted feeding are low-risk strategies that should be tested sooner than later."

The growing understanding of circadian rhythms also could offer help through what's known as chronotherapy.

The approach, known as chronotherapy, involves timing delivery of drugs to minimize side effects while maximizing effectiveness.

At the moment, there is only one chronotherapy clinical trial running in the United States.

Kuna, who runs a bowling alley in Johnsburg, Ill., opted to undergo chronotherapy at the nearby Block Center for Integrative Cancer Treatment in Skokie.