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Treatment with standard antibiotics amoxicillin and clindamycin caused dramatic shifts in the overall structure of bacterial populations in the mouse gut, diminishing the abundance several beneficial microbial groups, the team found.

On 3 December 2022 - a Saturday - there was a further missed opportunity to complete an x-ray; administer clindamycin and arrange for transfer to a tertiary centre for the purpose of undertaking a chest drain.

He said that on 29 November there was a "missed opportunity" to administer clindamycin, an antibiotic, which possibly contributed to Iona's death.

“Got an IV of clindamycin, Benedryl and acetaminophen.”

Although the shortage of amoxicillin, especially its liquid and chewable forms, has proved frustrating for pharmacists, doctors and parents whose children have grown accustomed to the bubble-gum and strawberry-flavored varieties of the drug, experts say there is no reason to panic: Supplies of effective alternatives like cephalexin and clindamycin remain plentiful, according to the F.D.A.