COENZYME A Definition & Meaning

coenzyme A

noun

Biochemistry.

a coenzyme, composed of a phosphorylated derivative of pantothenic acid linked to adenylic acid, that participates in the transfer of acyl groups in fatty acid metabolism and amino acid metabolism. : CoA

coenzyme A

noun

a constituent of biological cells that functions as the agent of acylation in metabolic reactions CoA

coenzyme A

A coenzyme that consists of a nucleotide linked to pantothenic acid (part of the vitamin B complex), is present in all living cells, and functions as an acyl group carrier. Coenzyme A is necessary for fatty acid synthesis and oxidation, pyruvate oxidation, and other acetylation reactions. In cellular respiration , each of two acetyl groups derived from the original glucose molecule attaches itself to coenzyme A as acetyl coenzyme A and then enters the Krebs cycle.

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�y��vlog History and Origins

Origin of coenzyme A¹

First recorded in 1935–40

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Example Sentences

Examples have not been reviewed.

Once taken into cells, it is converted into a molecule called coenzyme A, which can then be used in lots of metabolic pathways.

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Usually, it becomes linked to the molecule coenzyme A to form methylmalonyl-CoA, and is converted to succinyl-CoA in a reaction that involves vitamin B12 as a cofactor.

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He developed a new method of synthesizing nucleotides, and achieved international recognition for synthesizing coenzyme A, which is involved in converting fats to energy.

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He found coenzyme A which is a nucleotide containing phosphoric acid.

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