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The two can then coevolve, as happens in living organisms.

That means investigators can narrow down a protein’s shape by looking for amino acids that coevolve: Even if they are far apart on the unfolded chain, they are likely neighbors in the final 3D structure.

If the relationship between virus and fungus is as durable as it seems, it prompts fascinating questions about how the two microbes might coevolve, Dr. Romero Olivares said.

Thanks to this imperative, the seeds conserved on farms continue to coevolve with diverse pathogens and pests.

Then it suggests several other words you may have meant, including “coevolve,” “cavefish” and “goof-off.”