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The second pioneering tool employed was a novel application of cross-correlation to measure neuronal connectivity within a multi-electrode array system.

Previous studies that looked at hydrogen in the atmosphere of KELT-9b were able to see a strong hydrogen absorption line in the spectrum without doing a more complicated cross-correlation analysis like Heng and his team had to do to find iron and titanium.

This procedure was repeated for each of the 10 pairs of PSTHs, and the values of cross-correlation were averaged across all pairs.

Since the value of cross-correlation depended only on the ratios of the α parameters, not their magnitudes, we constrained the three parameters to the unit sphere.

These fits are for illustration purposes; the actual model maximized the cross-correlation of PSTHs by aligning them to a linear combination of tpress, trelease, and f.