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de novo
[ dee noh-voh, dey, dih; Latin de noh-woh ]
adverb
- anew; afresh; again; from the beginning:
We reviewed the court’s decision de novo during the rehearing.
- independently of external forces; from within; spontaneously:
Mutations associated with autism often occur de novo rather than through inheritance.
adjective
- occurring or arising spontaneously or independently of external forces; spontaneous: de novo synthesis of steroids from cholesterol.
de novo mutations;
de novo synthesis of steroids from cholesterol.
- made from scratch rather than developed from or based on something preexisting, and hence new, novel, or of a new type: de novo banks.
de novo protein design;
de novo banks.
- De No·vo, noting or related to a type of FDA classification allowing novel medical devices with no precedent on the market to be sold: De Novo classification.
a De Novo request;
De Novo classification.
de novo
/ diË Ëˆnəʊvəʊ /
adverb
- from the beginning; anew
˜yÐÄvlog History and Origins
Origin of de novo1
Example Sentences
Researchers are, therefore, trying to recreate them or to design so-called de novo proteins that do not occur in nature.
"These de novo or reference-guided assemblers are pretty well-established tools that entail a whole operational pipeline with repeat detection or structural variants' identification being just some of their functionalities," Segarra said.
However, de novo domesticated crops are likely to closely resemble their wild counterparts, which would make weeding challenging.
Today, scientists use advanced technology to design new synthetic drug compounds with the right properties and characteristics, also known as "de novo drug design."
The drug works by impairing one arm of purine production, the "de novo" pathway.
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