DENATURE Definition & Meaning

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denature

[ dee-ney-cher ]

Phonetic (Standard)IPA

verb (used with object)

denatured, denaturing.

to render (any of various alcohols) unfit for drinking by adding an unwholesome substance that does not alter usefulness for other purposes.
Biochemistry. to treat (a protein or the like) by chemical or physical means so as to alter its original state.
to make (fissionable material) unsuitable for use in an atomic weapon by mixing it with unfissionable material.
to deprive (something) of its natural character, properties, etc.

denature

/ diːˈneɪtʃəˌraɪz; diːˈneɪtʃə /

verb

to change the nature of
to change (a protein) by chemical or physical means, such as the action of acid or heat, to cause loss of solubility, biological activity, etc
to render (something, such as ethanol) unfit for consumption by adding nauseous substances
to render (fissile material) unfit for use in nuclear weapons by addition of an isotope

denature

/ ��ŧ-��′��ə�� /

To cause the tertiary structure of a protein to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
To cause the paired strands of DNA to separate into individual strands.

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Derived Forms

��ˌ�Բ��ٳܰ�ˈ��پ��ǲ�, noun
��ˈ�Բ��ٳܰ��Գ�, noun

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Other �y��vlog Forms

��·�Բ�·�ٳܰ�·��Գ� [dee-, ney, -cher-, uh, nt], noun
��·�Բ�·�ٳܰ�·��·�پ��ǲ� [dee-ney-ch, uh, -, rey, -sh, uh, n], noun

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�y��vlog History and Origins

Origin of denature¹

First recorded in 1675–85; de- + nature

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Example Sentences

Examples have not been reviewed.

It is thought that acids in the stomach denature the virus, said Michael Imperiale, a microbiologist and immunologist at the University of Michigan in Ann Arbor.

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However, when further testing was conducted — virus isolation — they were able to show it was inactivated virus that had been denatured by heat.

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Now that most of the paint is gone, spray the chair with denatured alcohol and scrub with more steel wool to clean off any residue.

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To manufacture the sponge, Mohammad Peydayesh, a senior scientist in Mezzenga's Group, and his colleagues denatured whey proteins under acidic conditions and high temperatures, so that they aggregated into protein nanofibrils in a gel.

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First, denatured alcohol and odorless mineral spirits are different things.

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