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Drs. Arnold E. Osterberg and Henry F. Helmholz of the Mayo Clinic reported experiments showing that ketonic bodies in the blood, such as acetone, diacetic acid and beta-oxybutyric acid, will cure such infections if generated in sufficient quantities.

Hence, when this function of the carbohydrates becomes impaired, these acids, Oxybutyric acid, Diacetic acid and Acetone, fail to be neutralized and are consequently absorbed into the blood stream, giving rise to a form of intoxication known as acidosis.

If the solution is boiled for two minutes, the color from diacetic acid will disappear, owing to the unstableness of that substance, while that from the drugs will remain unchanged.

Urine Tests.—It is advisable to make the tests in the morning; those for sugar and diacetic acid should be made every day or, in some cases, every other day, as directed by the physician, and those for ammonia and albumen about once a week.

The Giving of Alkalies.—If acidosis is evident, as may be indicated by an excretion of diacetic acid, oxybutyric acid, or acetone in the urine, alkalies may be given.