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Things began to go wrong only after Lisa was prescribed diazepam, which is typically used to treat anxiety, seizures or muscle spasms.

But the prosecution rejected that claim, saying the combined effects of alcohol and a "fixation" with diazepam, which he was buying off the streets, had sent him into a violent rage.

We found more than 100 examples of people trying to buy prescription medicines such as diazepam - commonly used to treat anxiety, muscle spasms and seizures - and instead receiving products containing nitazenes.

Doctors welcomed the reduction in the use of tramadol, pregabalin, and diazepam, but they also stressed that more needed to be done to ensure people could access other pain treatments more quickly.

In March, the BBC reported how Mr Durose had been prescribed diazepam for a chronic condition called hypermobility, which can cause fatigue, pain and stiffness in joints and muscles, and for joints to dislocate easily.