DOXORUBICIN Definition & Meaning

doxorubicin

[ dok-suh-roo-buh-sin ]

Phonetic (Standard)IPA

noun

Pharmacology.

a cytotoxic antibiotic, C 27 H 29 NO 11 , derived from a variety of the bacterium Streptomyces peucetius and used in the treatment of sarcoma, malignant lymphoma, acute leukemia, and other cancers: administered intravenously, it is noted for its bright red color and potentially dangerous side effects.

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�y��vlog History and Origins

Origin of doxorubicin¹

First recorded in 1970–75; d(e)ox(y)- + -o- + Latin rub(er) “red” (alluding to its color; rubric, red ¹ ) + -i- + -(my)cin

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Example Sentences

Examples have not been reviewed.

Published in the journal Cardiovascular Research, the WSU study focused on doxorubicin, a chemotherapy drug used to treat breast cancer, lymphoma, leukemia and other cancers.

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"What we're trying to do is to develop a method to locally deliver doxorubicin but also mitigate acidosis at the same time," Ahmed said.

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In the new work, the Leiden team tested two anthracycline variants that remove histones without breaking DNA: an approved cancer drug called aclarubicin, and a tweaked version of doxorubicin they call diMe-Doxo.

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Treatment with exosome-encased doxorubicin also shrank the tumours to a greater degree than did doxorubicin alone.

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The oncologist consulted us in cardio-oncology at Rush because there was concern her heart function would worsen with further doxorubicin treatment.

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