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The paper is titled "Activation of CBASS-Cap5 endonuclease immune effector by cyclic nucleotides."

But the challenge was how to introduce the endonuclease gene and its associated genetic payload to a spot in the genome where it would work safely without inadvertently affecting other aspects of the animal’s physiology.

It is the first drug in a new class called endonuclease inhibitors.

It is an endonuclease inhibitor; this is the first new class of influenza drugs to hit the market in over two decades.

Researchers need only an enzyme that cuts DNA, such as the endonuclease Cas9, and a guide RNA molecule that directs the enzyme to cut the gene of interest.