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But the deeper lesson in both their stories, one that recurs time and again, is the essentiality of being forthright with the other person about one’s history and identity, personal and political.

We search for signs of its essentiality, wondering whether it remains relevant in seasons devoid of superstars among its repertory players.

In their study, published today in the journal Genome Biology, the scientists used data from multiple genome-wide CRISPRi essentiality screens to train a machine learning approach.

"So unless you can prove Horizon's essentiality in your prosecution, then you are unlikely to get your conviction overturned," he added.

This "thought experiment" enabled them to calculate the "keystoneness" or the relative essentiality of each species in each community.