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familial hypercholesterolemia

noun

Pathology.
  1. an inherited metabolic disorder caused by a lack or malfunction of receptors for the low-density lipoproteins that activate removal of cholesterol from the blood. : FH.


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Example Sentences

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The study also examined Lynch syndrome, which raises the risk of colorectal and uterine cancers, and familial hypercholesterolemia, known for its impact on early-onset heart disease, heart attacks and stroke.

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As evidence, she points to studies of people with familial hypercholesterolemia—a condition that arises from a mutation in the gene encoding the LDL receptor protein.

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Riksen says some of the most direct evidence came from studying people with familial hypercholesterolemia, a genetic condition causing high levels of blood cholesterol.

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The test revealed she had familial hypercholesterolemia, an inherited condition that causes the body to churn out cholesterol.

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They include people like those in the study and people who have a genetic condition, familial hypercholesterolemia, that results in intractably high LDL levels and a grave risk of a heart attack.

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