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These include Huntington's disease, cystic fibrosis and some rare inherited cancer conditions.

It is thought more than 61,000 patients in the UK need it, including those with pancreatic cancer, cystic fibrosis and chronic pancreatitis.

The most obvious way that a pair of blood-related parents might increase health risks for a child is through a recessive disorder, like cystic fibrosis or sickle cell disease.

She died aged 46 on 18 December 2024, but will be remembered for "rewriting the book" on how to survive with cystic fibrosis, said her father, David John.

Long-term health effects can include lung cancer, pulmonary fibrosis or silicosis.