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The two molecular players work together to increase the breakdown of fatty acids and gluconeogenesis and inhibit the build-up of fats.

The backward flow—taking up two three-carbon molecules to make a sugar—is called gluconeogenesis.

In hummingbirds, loss of a key gene in gluconeogenesis makes their muscles very efficient at breaking down sugars for energy, a requirement for hovering flight.

In my case, and I presume many others, my gluconeogenesis response can occur in a relatively short time and at a relatively strong intensity, exhausting my natural insulin supply and raising my blood sugar to a dangerous level.

This is a well-studied process known as 'gluconeogenesis'.