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The film's slow descent into prosthetic-laced chaos cleverly uses the genre’s conventions to make a provocative point about the supposed “expiration” of feminine beauty, punctuated by the most gratuitous gross-out scene to grace the Academy’s ballot since “Triangle of Sadness”’s vomit cruise.

Yet, it’s disappointment that Perkins serves up most frequently in “The Monkey,” detouring from every wide-open chance to showcase depth and humanity in favor of juvenile humor and gross-out splatter gags.

The idea that you could see a weird gross-out movie with your family.”

More central than the gross-out factor is a wry statement of disability pride, a reminder that swagger needn’t be skin-deep.

“The Substance,” her Cannes-winning gross-out joke about an aging Hollywood actress with a high threshold for self-inflicted pain, boasts more butts per minute than a chainsmoker’s ashtray, a feat all the more monumental for the film’s nearly 2½-hour running time.