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Soliris, the drug at the center of the investigation, treats a rare blood disorder known as paroxysmal nocturnal hemoglobinuria.

The investigation was triggered, the company has said, by allegations a former employee made about the selling of Alexion’s flagship product, the Soliris treatment for a rare blood disorder known as paroxysmal nocturnal hemoglobinuria.

The terminal complement inhibitor is approved to treat the blood disorder known as paroxysmal nocturnal hemoglobinuria and the genetic disorder called hemolytic uremic syndrome.

Lignières has found in hemoglobinuria a streptococcus which produced nephritis, bloody urine, and paraplegia in experimental animals, including horses.

Winckel's disease, or epidemic hemoglobinuria, is a very fatal affection, sometimes epidemic in lying-in institutions; it develops about the fourth day after birth.