HYBRIDOMA Definition & Meaning

hybridoma

[ hahy-bri-doh-muh ]

Phonetic (Standard)IPA

noun

Biotechnology.

plural hybridomas.

a hybrid cell made in the laboratory by fusing a normal cell with a cancer cell, usually a myeloma or lymphoma, in order to combine desired features of each, as the ability of the cancer cell to multiply rapidly with the ability of the normal cell to dictate the production of a specific antibody.

hybridoma

/ ˌ��ɪ��əˈ��əʊ��ə /

noun

a hybrid cell formed by the fusion of two different types of cell, esp one capable of producing antibodies, but of limited lifespan, fused with an immortal tumour cell

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�y��vlog History and Origins

Origin of hybridoma¹

First recorded in 1975–80; hybrid + -oma

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�y��vlog History and Origins

Origin of hybridoma¹

C20: from hybrid + -oma

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Example Sentences

Examples have not been reviewed.

The accidental loss of hybridoma cell lines is especially detrimental as genetic material might be unavailable to recover the coding sequence for continued antibody use.

From

Spleen cells that had been activated upon antigen recognition fused preferentially with the myeloma cells, generating hybrid cells called hybridomas.

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Soll sits on the largest noncommercial hybridoma bank in the world.

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Although for many years the path toward this goal appeared to be pharmacologic in nature, four decades ago an important deviation was made: the advent of hybridoma technology.

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Unlike unfused cells, the hybridoma cells could grow on the selective agar plates used, and formed colonies of identical cells.

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