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Gout is a common type of inflammatory arthritis caused by a condition called hyperuricemia — when there’s too much uric acid in a person’s bloodstream, said Dr. Erin Bauer, a rheumatologist at Virginia Mason Medical Center and board co-chair of the Arthritis Foundation’s Great West Region.

An anonymous source - said to be "familiar with North Korea affairs" - quoted by the South Korean news agency Yonhap, said he understood Mr Kim was "suffering from gout, along with hyperuricemia, hyperlipidemia, obesity, diabetes and high blood pressure".

Ardea is currently developing the drug lesinurad, which is in Phase III development as a potential treatment for the management of hyperuricemia in gout patients.

Deerfield-based subsidiary, Takeda Pharmaceuticals North America Inc., markets oral diabetes, sleep, gastroenterology, cholesterol lowering treatments as well as drugs for chronic management of hyperuricemia in patients with gout, and through the Takeda Global Research & Development Center Inc.Takeda in May agreed to buy Nycomed for $13.7 billion at the time, to boost its presence in emerging markets and add a new lineup of drugs.

The first is hyperuricemia, the buildup of uric acid in the bloodstream, which happens when the body breaks down purines - DNA building blocks that are particularly high in certain meats, shellfish and beer.