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They discovered that disruption of the internal clock in the epithelial cells lining the intestine alters secretion of cytokine proteins, leading to heightened inflammation, increased numbers of immunosuppressive myeloid cells and cancer progression.

Glioblastoma is inherently dangerous due to its location in the brain and its immunosuppressive tumor microenvironment, which renders glioblastoma resistant to promising immunotherapies.

But the transplants are risky and require lifelong immunosuppressive drugs.

He and his team began testing its immunosuppressive applications, and realized that the drug could be the cheap and effective solution they’d been looking for.

Patients undergoing chemotherapy or immunosuppressive treatments after organ transplant often present compromised immune systems.