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Hormones are these internal secretions that come out of a gland, and they go through the blood, but they go to a specific target.

In many cases the internal secretion is no mere accumulation, e.g. the internal skeleton of the Radiolaria, and the nematocysts of the Coelentera.

It is generally believed that the internal secretion of the thyroid and the adrenal are antagonistic.

One, that of ovulation, is so prominent that the other, the internal secretion, has been too much neglected.

This was the first time in physiology that the idea of an internal secretion was advanced.