�y��vlog

Medtronic allegedly sponsored the events over a nine-year period to persuade Asfora to use Medtronic products, namely its SynchroMed II intrathecal infusion pumps, which are implantable devices used to deliver medication to patients.

Drugs can be injected directly into the intrathecal spaces in the spinal cord.

Another drawback of most antisense oligonucleotide therapies targeting the brain is that they typically require an intrathecal injection, similar to a spinal tap, which makes many patients uneasy.

“It must not be used by the intrathecal, epidural, intravenous or any other unspecified routes,” the company wrote.

Devices such as spinal cord stimulators can be implanted that generate electrical pulses to the nerves to alleviate pain or intrathecal pumps can deliver pain medications directly into the spinal fluid.