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By the time Columbus landed, indigenous populations in Central and South American were utilizing ipecacuanha, a root found in Brazil with expectorant and emetic properties and balsam, which is still used in some cold remedies today.

Here is Yeats on the flighty mother of an artist friend: “She makes me think of lumpy beds, Russian fleas and ipecacuanha wine.”

His grandfather introduced the use of ipecacuanha; his father was first physician to Queen Marie Leczinska of France.

A citizen, who said he felt dry after working so hard all day, regaled himself with a pint bottle of Ipecacuanha wine, and left immediately after it was down, to see how the fire was getting along in another place.

If ever there existed any reason for the administration of an emetic—and ipecacuanha has generally been used at the commencement of an attack of cholera—it must be looked for, not in any clinical experience of its virtues, but simply in the deplorable routine that required the administration of an emetic at the commencement of nearly all acute diseases, so that, whatever else was prescribed, the lancet and an emetic seldom failed to be so.