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A very irritable heart results not infrequently from cigarette smoking but such is almost always found in young men in whom the lesions of arteriosclerosis are exceedingly rare.

Irritable Heart of Athletes.—A curiously interesting form of heart neuroses has appealed to me very much because I have suffered somewhat from it myself and owing to circumstances I think I have seen a larger number of patients suffering from it than usually come to a single individual.

Naughty Brain— George Washington Crile of Cleveland said that the frontal lobe, the thinking part of the brain, is the naughty contributing cause of stomach ulcer, exophthalmic goiter, irritable heart, and possibly diabetes—all diseases to which high-strung, emotionally and physically active persons are prone.

The man had an apparently feeble and irritable heart; cold, clammy skin; disturbed digestion, and uneasy sleep; was constipated and flatulent.

The "irritable heart," the "tobacco heart," a life of promise impaired or blighted.