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The medical cause of death was recorded as acute intestinal ischaemia, a medical emergency caused by the blood flow to the bowel being restricted.

The pathologies of heart conditions are complex and interwoven, but they often start with ischaemia.

Alarcon-Martinez et al. investigated the role of IP-TNTs in this process by blocking the central retinal arteries of mice or inducing local ischaemia with a laser.

“There’s also unpublished data showing that miR-92A can improve heart function in diabetic pigs with chronic ischaemia,” she says.

So far, only three treatments have earned conditional approval: one for spinal-cord injury, one for heart disease and one for critical limb ischaemia, a painful condition characterized by reduced blood flow to the extremities.