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"Knowledge of Bernoulli's law, the ideal gas law, and isothermal expansion are the three ingredients we baked into a model to explore how this device worked," Lipscombe said.

"But when it's in that isothermal layer... between the surface and 180 metres... the sound behaves really quite straight."

The pilot will also make use of “LAMP”, or loop mediated isothermal amplification, which the government described as a new type of testing technology able to deliver significant volumes of tests.

But there’s another approach to gene-based testing, called isothermal amplification, which is simpler and can work at a fixed temperature.

The authors provided evidence that darobactin and BamA bind to each other directly, using a technique called isothermal titration calorimetry, which measures the heat changes associated with physical interactions between molecules.