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The seat of greatest congestion will always be found in the neighborhood of the toe, because of the increased vascularity of that part, and, although at times it is limited to the podophyllous tissue alone, any or all parts of the keratogenous membrane may be affected by the congestion and followed finally by inflammation.

Where the lameness is but slight, we may attribute it almost solely to the pain occasioned by the mere wounding of the keratogenous membrane, and to no very extensive inflammatory changes therein.

It will here be seen that the injury to the keratogenous membrane has led to great interference with the secretion of horn from the sensitive laminæ.

The horn of the wall must be removed, and the diseased structures, whether gangrenous keratogenous membrane, necrosed ligament, or carious bone, carefully excised or curetted.

Causes.—Seeing that this accident to, and consequent severe wounding of, the keratogenous membrane nearly always occurs in but one way, it is worthy of special mention.