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Rare disorders called lipodystrophy syndromes illustrate this vividly.

The disease “may be classified as a form of lipodystrophy or progeria because of its overlapping symptoms,” which includes the appearance of premature aging, according to the site.

I do exercises to help get a better shape, to help reduce my lipodystrophy: body bulge is a common side-effect.

For example, it has an entry about “bitrochanteric lipodystrophy,” a real disorder in which fat deposits gather in one’s hips and buttocks in a ghastly way.

But people with lipodystrophy had the most severe insulin resistance he had ever seen, and they were far from obese.