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In all species that have an appendix, Smith notes, it either contains or is closely associated with lymphoid tissue, which plays a role in supporting the immune system.

In all, three recipients of transfusions developed the disease and a fourth had abnormal prions in his lymphoid tissue when he died.

The dictionary said: Any of the various malignant tumors that arise in the lymph nodes or in other lymphoid tissue.

Both areas are made of the same lymphoid tissue at particular risk for HPV infection, and are part of what specialists call Waldeyer’s Ring.

But they did make one interesting discovery: Species who had an appendix tend to have higher concentrations of lymphoid tissue in their cecum, a pouch that connects the small and large intestine.