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“Orders were to continue using the insulin pump, confirm metformin dose and add blood sugar checks,” the autopsy findings show.

"The anti-inflammatory effect of metformin interested us, as MPNs are very inflammatory diseases. This is the first study to investigate the association between metformin use and risk of MPN."

The results “could be a tipping point” that convinces doctors to prescribe metformin to treat COVID, said Dr. Carolyn Bramante, the lead U researcher of the drug trial.

It would also be possible to estimate whether another treatment plan would be better, for example, than the commonly prescribed medication, metformin.

However, there are currently only a few studies on the long-term effects of metformin on the health of offspring.