˜yÐÄvlog

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methotrexate

[ meth-oh-trek-seyt ]

noun

Pharmacology.
  1. a toxic folic acid analogue, C 2 0 H 2 2 N 8 O 5 , that inhibits cellular reproduction, used primarily in the treatment of psoriasis and certain cancers and as an immunosuppressive agent.


methotrexate

/ ËŒmɛθəʊˈtrÉ›kseɪt; ËŒmiËθəʊ- /

noun

  1. an antimetabolite drug used in the treatment of certain cancers. Formula: C 20 H 22 N 8 O 5
“Collins English Dictionary — Complete & Unabridged†2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

methotrexate

/ ³¾Ä•³Ù³ó′ə-³Ù°ùÄ•°ì′²õÄå³Ù /

  1. A toxic drug that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases, such as rheumatoid arthritis. Chemical formula: C 20 H 22 N 8 O 5 .
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˜yÐÄvlog History and Origins

Origin of methotrexate1

1950–55; metho(xy)- + trexate, of unclear derivation
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Example Sentences

Examples have not been reviewed.

The researchers also showed that the gamma treatment improved the signs of chemo brain in mice that received a different chemotherapy drug, methotrexate, which is used to treat breast, lung, and other types of cancer.

From

Published in The Lancet, the paper investigated methotrexate, a low-cost, effective treatment for inflammatory joint conditions such as rheumatoid arthritis and psoriatic arthritis.

From

The patients were given oral doses of methotrexate or ciclosporin and assessed over nine months of treatment and six months after the therapy ended.

From

Isabella McDonald, then a junior at Utah Valley University, was diagnosed in April with a rare, often fatal bone cancer, whose sole treatment for young adults includes the drug methotrexate.

From

A good example is the use of methotrexate, which is the standard treatment for ectopic pregnancy.

From

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