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microcephaly

/ ˌmaɪkrəʊsɪˈfælɪk; ˌmaɪkrəʊˈsɛfəlɪ /

noun

  1. the condition of having an abnormally small head or cranial capacity Compare megacephaly
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012


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Derived Forms

  • ˌˈ󲹱dzܲ, adjective
  • microcephalic, adjectivenoun
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Example Sentences

Examples have not been reviewed.

Known as Oropouche virus, it can trigger a fever that may cause pregnant people to miscarry or their babies to have birth defects known as microcephaly, or smaller than usual heads.

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That’s because an infection during pregnancy can cause microcephaly, which is when a baby's head is much smaller than expected, and other congenital malformations like limb contractures, high muscle tone, eye abnormalities, and hearing loss.

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The team's finding suggests that maintaining the neuronal NMD function is essential for early brain development to prevent microcephaly.

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"In many cases, animal models simply do not recapitulate either the characteristics or the degree of severity seen in human brain diseases such as microcephaly," Song said.

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It's hoped the milestone findings will provide a deeper understanding into the protein's impact on healthy development and lead to treatments that can slow or stop the development of microcephaly and potentially other neurological disorders.

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