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Institute in Zagreb, Croatia, provided expertise in comparative genomics and mitotic spindle geometry and biophysics, respectively.

This migration occurs because the chromosomes are attached to a cellular machine known as the mitotic spindle.

The microtubule-based mitotic spindle segregates chromosomes during cell division.

Mitotic defects result in inaccurate partitioning of whole chromosomes between daughter cells — mediated through incorrect attachment of chromosomes to the mitotic spindle.

Among its functions, this protein regulates the mitotic spindle and hence the crucial balance between cell proliferation and differentiation – vital not only for cancer, but also for correct brain development.