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osteoclast

[ os-tee-uh-klast ]

noun

  1. Cell Biology. one of the large multinuclear cells in growing bone concerned with the absorption of osseous tissue, as in the formation of canals.
  2. Surgery. an instrument for effecting osteoclasis.


osteoclast

/ ˈɒɪəʊˌæ /

noun

  1. a surgical instrument for fracturing bone
  2. a large multinuclear cell formed in bone marrow that is associated with the normal absorption of bone
“Collins English Dictionary — Complete & Unabridged” 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

osteoclast

/ ŏŧ-ə-ă′ /

  1. A specialized bone cell that absorbs bone, allowing for the deposition of new bone and maintenance of bone strength. Osteoclasts secrete enyzmes that dissolve the matrix of old bone tissue and acids that dissolve bone salts, which contain calcium and phosphorus. Except in growing bone, the rate of bone deposition and bone absorption equal each other so that bone mass remains constant. A mass of osteoclasts absorbs bone from the outer surfaces inward for about three weeks. The osteoclasts are then converted into osteoblasts that form new bone to fill in the cavities.
  2. See also osteoblast
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Derived Forms

  • ˌDzٱˈپ, adjective
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Other yvlog Forms

  • Dzt··t adjective
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yvlog History and Origins

Origin of osteoclast1

1870–75; osteo- + -clast < Greek ó broken
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Compare Meanings

How does osteoclast compare to similar and commonly confused words? Explore the most common comparisons:

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Example Sentences

Examples have not been reviewed.

However, PTH induction is also associated with the differentiation of macrophages into osteoclasts, which are specialized cells responsible for bone resorption.

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Osteoblasts and osteoclasts are two types of cells crucial for the maintenance and remodeling of bone tissue.

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The researchers also investigated PEPITEM's effect on osteoclasts and bone resorption.

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Inspired by the traditional efficacy of female ginseng, the team tested the compounds for their impact on the formation of cells called osteoclasts, which facilitate bone loss.

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In both types of spinal degeneration, they saw a strong association between the presence of senescent osteoclasts and the degree of degeneration and spine hypersensitivity.

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