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These mutations, which prevent the p53 protein from forming a tetramer -- an assembly of four p53 proteins -- had been studied before, using a technique that involves inserting artificial copies of a mutated p53 gene into a cell.

In around 30 percent of all cases of breast cancer, the cancer cells show mutations or losses in the p53 gene.

Another obvious example would be the p53 gene, which is very strongly associated with cancer suppression.

It's possible that multiple copies of the p53 gene evolved to protect elephant sperm from hot temperatures.

Other large animals don't have multiple copies of the p53 gene.