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From the base often near its middle arises one large fibre—the axone fibre, which conducts impulses away from the perikaryon.

In some few cells the axone breaks up into branches in the immediate neighbourhood of its own perikaryon in the cortex.

The figure as interpreted in terms of functional conduction means that the cortex is beset with conductors, each of which collects nerve-impulses, from a minute but relatively wide field by its branched dendrites, and that these nerve-impulses converge through its perikaryon, issue by its axone, and are carried whithersoever the axone runs.

The cortical neurone therefore collects impulses in the region of cortex just about its perikaryon and discharges them to other regions, some not cortical or even cerebral, but spinal, &c.

It is noteworthy that the dendrite fibres of these cortical neurones do not transgress the limits of the grey cortex and the immediate neighbourhood of the perikaryon to which they belong; whereas the discharging or axone fibre does in the vast majority of cases transgress the limits of the grey matter wherein its perikaryon lies.