PHARMACOKINETICS Definition & Meaning

pharmacokinetics

[ fahr-muh-koh-ki-net-iks, -kahy- ]

Phonetic (Standard)IPA

noun

(used with a singular verb)

the branch of pharmacology that studies the fate of pharmacological substances in the body, as their absorption, distribution, metabolism, and elimination.

pharmacokinetics

/ ˌfɑːməkəʊkɪˈnɛtɪsɪst; -kaɪ-; ˌfɑːməkəʊkɪˈnɛtɪks /

noun

the branch of pharmacology concerned with the way drugs are taken into, move around, and are eliminated from, the body

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Derived Forms

pharmacokineticist, noun
ˌ��󲹰��ǰ쾱ˈ�Ա�پ��, adjective
ˌ��󲹰��ǰ쾱ˈ�Ա�پ��ally, adverb

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�y��vlog History and Origins

Origin of pharmacokinetics¹

First recorded in 1955–60; pharmaco- + kinetics

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Example Sentences

Examples have not been reviewed.

A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug.

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"In terms of potency, it will be hard to improve the molecule any further, but there are many other properties to consider and optimize, for example, pharmacokinetics, metabolism and aqueous solubility," says Kitamura.

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One way to try to counteract the variability in chemotherapy pharmacokinetics is a strategy called therapeutic drug monitoring, in which the patient gives a blood sample at the end of one treatment cycle.

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She was among 16 advisers who said trial data and pharmacokinetics, a branch of science that studies the movement of drugs in the body, brought them to a clear conclusion about the oral drugs.

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“The pharmacokinetics of miniproteins”—the ways the human body can metabolize, absorb and excrete them—“will be a barrier to their usefulness as drugs,” Procko says.

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