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Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients.

Like quinine, it arrests the normal amoeboid movements of the polymorphonuclear leucocytes, and has a definite antiperiodic action; but it is a very poor substitute for quinine in malaria.

The Polymorphonuclear Cell.—This possesses a nucleus of very complicated outline and a fair amount of protoplasm filled with numbers of fine granules which stain with eosin.

The polymorphonuclear and eosinophile cells are derived from the bone-marrow, each by division of specific mother cells located in that tissue.

In the one form these are lymphocytes, which are found in health mainly in the marrow, the blood itself, the lymph glands and in the lymphatic tissue round the alimentary canal; in the other they are the kinds of leucocytes normally found in the bone-marrow-myelocytes, neutrophile, basophile and eosinophile, and polymorphonuclear cells, also neutrophile, basophile and eosinophile.